One option that I've seen implemented in a few shops is available to you if you have UNIX skills and you already have a UNIX site license for one of the enterprise AV products. These shops have ported the UNIX AV product to OS/400 and run it in OS/400's PASE environment.
Finally, the easiest option is to run the AV product that runs natively on OS/400 that's available from Bytware.
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